The USAF Counterproliferation Center was established in 1998 at the direction of the Chief of Staff of the Air Force. Located at Maxwell AFB, this Center capitalizes on the resident expertise of Air University, while extending its reach far beyond - and influences a wide audience of leaders and policy makers. A memorandum of agreement between the Air Staff Director for Nuclear and Counterproliferation (then AF/XON), now AF/A5XP) and Air War College Commandant established the initial manpower and responsibilities of the Center. This included integrating counterproliferation awareness into the curriculum and ongoing research at the Air University; establishing an information repository to promote research on counterproliferation and nonproliferation issues; and directing research on the various topics associated with counterproliferation and nonproliferation .

The Secretary of Defense's Task Force on Nuclear Weapons Management released a report in 2008 that recommended "Air Force personnel connected to the nuclear mission be required to take a professional military education (PME) course on national, defense, and Air Force concepts for deterrence and defense." As a result, the Air Force Nuclear Weapons School, in coordination with the AF/A10 and Air Force Global Strike Command, established a series of courses at Kirtland AFB to provide continuing education through the careers of those Air Force personnel working in or supporting the nuclear enterprise. This mission was transferred to the Counterproliferation Center in 2012, broadening its mandate to providing education and research to not just countering WMD but also nuclear deterrence.

The CPC's military insignia displays the symbols of nuclear, biological, and chemical hazards. The arrows above the hazards represent the four aspects of counterproliferation - counterforce, active defense, passive defense, and consequence management.

What is Counterproliferation?